Hamas said its fighters fired an anti-tank missile at an Israeli tank in southwest Khan Younis.
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The Israeli military said it killed at least 11 gunmen who tried to plant explosives near troops and others who fired rifles and rocket-propelled grenades at soldiers in Khan Younis.
The Hamas-allied Palestinian group Islamic Jihad said its fighters attacked Israeli forces in the area and fired rockets into Israel.
Gaza's Health Ministry said Israeli strikes hit the area surrounding Al-Amal Hospital and the largest functioning medical facility in the south, Nasser Hospital.
The Israeli bombing is endangering health care and endangering the lives of doctors, patients and displaced people, said ministry spokesman Ashraf Al-Qidra.
The Israeli military says it is in contact with hospital directors and medical staff by telephone and on site to ensure they are operational and accessible. Israel says Hamas operates in and around medical facilities, a claim the group denies.
In a ruling Friday, the World Court refrained from ordering a ceasefire but ordered Israel to prevent genocide against Palestinians and do more to help civilians. Prime Minister Benjamin Netanyahu said afterwards that the war to destroy Hamas would continue.
In the southern city of Rafah, 57-year-old Zainab Khalil, who was displaced several times with her family until they found refuge near the border with Egypt, said the ICJ ruling was important but not enough. “We want a ceasefire now,” she said.
Israel launched its air, sea and land offensive after militants from the Hamas group that rules Gaza stormed Israel on October 7, killing 1,200 people and kidnapping 253.
Some 26,257 Palestinians have been killed and nearly 65,000 injured so far, including 174 in the last 24 hours, Gaza health authorities said on Saturday. Most of the enclave's 2.3 million residents were displaced.
According to Israel, 220 soldiers have died since the ground offensive began. It is said to have killed at least 9,000 Gaza fighters so far, a figure which Hamas has rejected.
Residents and Hamas fighters reported fighting on Saturday in the central and northern parts of the enclave, where heavy rain flooded the tents of displaced people and forced some to seek alternative shelters in the middle of the night.
In Rafah, where more than half of Gaza's population is currently sheltering in shelters and tents, the Gaza Strip Health Ministry said an Israeli airstrike killed three people in a house there.
It was not immediately clear who the victims were and there was no immediate comment from the Israeli military.
In the occupied West Bank, a man was killed in a shootout with Israeli forces near Jenin, residents said.